
If you’ve been dealing with an underactive thyroid, commonly known as hypothyroidism, you may be surprised to learn that it can also increase your risk of developing a different health condition – fatty liver disease.
This connection between thyroid function and liver health is not widely known, but understanding it can be crucial for your overall well-being.
The key question now is “Can Low Thyroid Function Increase Fatty Liver Disease risk?”
Key Takeaways:
What is Fatty Liver Disease?
Fatty liver disease, also called hepatic steatosis, is a condition where fat accumulates in the liver. This can happen for various reasons, but one of the lesser-known contributors is an underactive thyroid.
Fatty liver disease can take two forms: non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
NAFLD is the more common and less severe form, while NASH involves inflammation and can potentially lead to more serious liver damage, such as cirrhosis or liver cancer.
Also Read: 7 Fatty Liver Disease Symptoms You Can’t Afford to Miss
Top 5 Liver Support Supplements of 2025
If you’re looking to improve your liver health and reduce symptoms like bloating and fatigue, choosing the right supplement is key. After extensive research and analysis, we’ve identified the top liver health products for 2025.
Below, we provide a detailed side-by-side comparison of these supplements, highlighting their strengths and weaknesses.

Best Overall: ⭐⭐⭐⭐⭐ (9.8/10)
- Clinically tested in a placebo-controlled trial by Princeton Consumer Research.
- Contains all 5 must-have ingredients for liver support.
- 90% of participants reported reduced bloating within two weeks*
- Free from fillers and artificial additives
- Vegetarian, non-GMO, and gluten-free
- Made in the USA
LivCare Support by Nutreance earned our #1 ranking because it is the only liver health supplement that meets every one of our strict criteria.
It includes all five essential ingredients for liver health—N-Acetyl Cysteine (NAC), Milk Thistle (standardized to 80% silymarin), Choline Bitartrate, Dandelion Root, and Artichoke Leaf—while being free from additives.
For the best prices and shipping, we recommend purchasing directly from LivCare Support’s official website, where additional discounts are available. Click here to visit the product website.

Rating #2: ⭐⭐⭐⭐☆ (9.7/10)
- Contains 4 out of 5 must-have ingredients
- Low-dose, high-efficiency formula
- Supports liver detoxification
- Available in 2 sizes
- 90-Day Money-Back Guarantee.
- No artificial additives
- Enhances bile production for better digestion
Why Ultra Liver #2: It’s a strong contender, featuring milk thistle, choline, dandelion root, and artichoke leaf. However, its lack of N-acetyl cysteine and lower silymarin content make it less comprehensive than Liver Flow Plus.
For the best prices and shipping, we recommend purchasing directly from Ultra Liver’s official website, where additional discounts and products are available. Click here to visit the product website.

Rating #3: ⭐⭐⭐☆☆ (9.5/10)
- Includes 3 core ingredients: N-acetyl cysteine, silymarin, and artichoke leaf.
- Detoxify and Restore healthy liver
- 90-Day Money-Back Guarantee.
- Free of artificial additives.
- Highly praised by customers and supported by excellent service.
- Vegan, non-GMO, and gluten-free
Why GlycoFortin Ranked #3: LivCare by Ortho Molecular Products provides effective liver support with a strong cast of ingredients that features 4 of the primary components that we look for in a quality liver supplement: milk thistle, choline bitartrate, dandelion root, and artichoke leaf.
Verdict: For the best prices and shipping, we recommend purchasing directly from GlycoFortin’s official website, where additional discounts and products are available. Click here to visit the product website.

Rating #4: ⭐⭐⭐☆☆ (8.7/10)
- Contains 3 out of 5 must-have ingredients
- Features N-acetyl cysteine and milk thistle.
- 60-Day Money-Back Guarantee.
- Vegetarian, non-GMO, and gluten-free
- Made in the USA
- ❌ Does not contain choline or dandelion
- ❌ Slightly larger than average size capsule
Rating: ⭐⭐⭐☆☆ (8.7/10)
Why Urgent Liver 911 Ranked #4: Unfortunately, Urgent Liver 911 does not contain choline or dandelion root, both of which are critical to help flush harmful toxins and fats out of the liver. It also has not been evaluated for efficacy in a clinical study.
Verdict: Contains high doses of vitamins and minerals that are likely to conflict with a daily multivitamin. Click here to visit the product website.

Rating #5: ⭐⭐☆☆☆ (8.5/10)
- Contains 2 out of 5 must-have ingredients
- No artificial additives
- Non-GMO and gluten-free
- ❌ No clinical study
- ❌ Does not contain N-acetyl cysteine, choline, or dandelion
- ❌ Contains some ingredients without sufficient evidence of efficacy
Why Triple liver Health Ranked #5: Limited effectiveness. Does not provide minimum effective doses of some ingredients. This product is also unsuitable for vegetarians due to its ox bile content.
Triple Liver Health includes two powerful detoxifiers—N-acetyl cysteine and milk thistle. However, its lack of choline, dandelion root, and artichoke reduces its overall effectiveness. (1) The milk thistle is standardized to 30% silybins, a key flavonoid complex within silymarin, ensuring a focus on its most active components.
Verdict: A basic option that lacks comprehensive healthy liver support. Click here to visit the product website.bsite.
How is Thyroid Function Linked to Fatty Liver Disease?
Thyroid hormones play a crucial role in regulating your body’s metabolism and fat storage.
When thyroid function is impaired, as in the case of hypothyroidism, this can disrupt the normal balance of fat metabolism and lead to the accumulation of fat in the liver.
Specifically, hypothyroidism can contribute to fatty liver disease in the following ways:
1. Decreased Metabolism
Thyroid hormones are responsible for regulating your body’s metabolic rate. When thyroid function is low, your metabolism slows down, making it harder for your body to break down and process fats effectively. This can lead to the buildup of fat in the liver.
2. Increased Fat Storage
Thyroid hormones also play a role in the way your body stores and distributes fat. In hypothyroidism, the body may be more prone to storing excess fat, including in the liver.
3. Insulin Resistance
Hypothyroidism can contribute to insulin resistance, a condition where your cells become less responsive to the hormone insulin. This can lead to the development of fatty liver disease, as insulin resistance is a major risk factor for NAFLD.
Symptoms and Diagnosis
The symptoms of fatty liver disease can be quite subtle, and in many cases, the condition may not cause any noticeable symptoms at all, especially in its early stages. Some potential symptoms include:
- Fatigue
- Abdominal discomfort or pain
- Nausea
- Swelling in the legs or abdomen
To diagnose fatty liver disease, your healthcare provider may order one or more of the following tests:
- Blood tests to check for elevated liver enzymes
- Imaging tests like ultrasound, CT scan, or MRI to detect fat accumulation in the liver
- Liver biopsy, which involves taking a small sample of liver tissue for analysis
It’s important to note that the presence of hypothyroidism does not automatically mean you will develop fatty liver disease.
However, if you have an underactive thyroid, it’s a good idea to discuss your risk with your healthcare provider and consider regular monitoring of your liver health.
WATCH THIS VIDEO: Can Low Thyroid Function Increase Fatty Liver Disease risk?

Managing Thyroid Function and Fatty Liver Disease
If you have been diagnosed with both hypothyroidism and fatty liver disease, there are steps you can take to address both conditions and potentially reduce your health risks.
Treat Hypothyroidism
The first step is to ensure that your hypothyroidism is properly managed through the use of thyroid medication, such as levothyroxine.
This can help restore your thyroid function to normal levels and may, in turn, help prevent or slow the progression of fatty liver disease.
Maintain a Healthy Lifestyle
In addition to addressing your thyroid condition, adopting a healthy lifestyle can also be beneficial for managing fatty liver disease. This includes:
Regular Monitoring
Because of the connection between thyroid function and liver health, it’s important to have regular check-ups with your healthcare provider.
This may involve periodic blood tests to monitor your thyroid and liver function, as well as periodic imaging tests to assess the status of your liver.
Frequently Asked Questions (FAQs)
1. Can hypothyroidism cause fatty liver disease?
Yes, hypothyroidism, or an underactive thyroid, can contribute to the development of fatty liver disease. The link is related to the role thyroid hormones play in regulating metabolism and fat storage.
2. How does thyroid dysfunction affect the liver?
Thyroid hormones are essential for maintaining proper liver function. When thyroid function is impaired, as in the case of hypothyroidism, it can disrupt the normal balance of fat metabolism, leading to the accumulation of fat in the liver.
3. Is there a connection between Hashimoto’s thyroiditis and fatty liver disease?
Yes, there is a potential connection. Hashimoto’s thyroiditis is an autoimmune disorder that can cause hypothyroidism.
The impaired thyroid function associated with Hashimoto’s may contribute to the development of fatty liver disease.
4. Can treating hypothyroidism improve fatty liver disease?
Yes, addressing hypothyroidism through proper treatment and medication may help reduce the risk or progression of fatty liver disease.
Restoring normal thyroid function can help regulate metabolism and fat storage, which can in turn improve liver health.
5. Should people with hypothyroidism get their liver function tested?
Yes, it is generally recommended for individuals with hypothyroidism to have their liver function tested regularly.
This is because of the potential link between thyroid dysfunction and fatty liver disease. Regular monitoring can help detect any liver-related issues early on.
6. Can weight loss help with fatty liver disease in people with hypothyroidism?
Yes, maintaining a healthy body weight through a balanced diet and regular exercise can be beneficial for individuals with both hypothyroidism and fatty liver disease.
Weight loss can help reduce the amount of fat accumulation in the liver and improve overall liver health.
7. Is there a specific diet recommended for people with hypothyroidism and fatty liver disease?
There is no one-size-fits-all diet, but a generally healthy, balanced diet that is low in added sugars, refined carbohydrates, and unhealthy fats may be beneficial for both hypothyroidism and fatty liver disease.
Focusing on nutrient-dense whole foods, lean proteins, and healthy fats can help support overall metabolic and liver health.
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